Title : Antipsychotics and cognitive decline in Alzheimer's disease: the LASER-Alzheimer's disease longitudinal study - Livingston_2007_J.Neurol.Neurosurg.Psychiatry_78_25 |
Author(s) : Livingston G , Walker AE , Katona CL , Cooper C |
Ref : Journal of Neurology Neurosurg Psychiatry , 78 :25 , 2007 |
Abstract :
OBJECTIVE: To investigate in a longitudinal cohort of people with Alzheimer's disease whether taking antipsychotics is associated with more rapid cognitive deterioration. METHOD: From a sample of 224 people with Alzheimer's disease recruited as epidemiologically representative, those taking antipsychotic drugs for more than 6 months were compared with those who were not, in terms of change in three measures of cognition. The effects of potential mediators and confounders (demographic factors, neuropsychiatric symptoms, cognitive severity and cholinesterase inhibitors) were also examined. |
PubMedSearch : Livingston_2007_J.Neurol.Neurosurg.Psychiatry_78_25 |
PubMedID: 16801350 |
Livingston G, Walker AE, Katona CL, Cooper C (2007)
Antipsychotics and cognitive decline in Alzheimer's disease: the LASER-Alzheimer's disease longitudinal study
Journal of Neurology Neurosurg Psychiatry
78 :25
Livingston G, Walker AE, Katona CL, Cooper C (2007)
Journal of Neurology Neurosurg Psychiatry
78 :25