| Title : Asperbenzophenone A and Versicolamide C, New Fungal Metabolites from the Soft Coral Derived Aspergillus sp. SCSIO 41036 - Long_2022_Chem.Biodivers__e202100925 |
| Author(s) : Long J , Pang X , Lin X , Liao S , Zhou X , Wang J , Yang B , Liu Y |
| Ref : Chem Biodivers , :e202100925 , 2022 |
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Abstract :
Two new compounds, asperbenzophenone A (1) and versicolamide C (5), together with fifteen known compounds were isolated from a soft coral derived fungus Aspergillus sp. SCSIO 41036. Their structures were elucidated by spectroscopic methods, ECD analysis, and by a comparison with data from the literature. In bioassay, compound 8 showed significant inhibitory activity against lipopolysaccharide-inducted nitric oxide (NO) in RAW264.7 cells at the concentration of 10microM. Additionally, the anti-acetylcholinesterase activity assay showed that 14 exhibited weak inhibition with an IC(50) value of 157.8microM. |
| PubMedSearch : Long_2022_Chem.Biodivers__e202100925 |
| PubMedID: 35194907 |
Long J, Pang X, Lin X, Liao S, Zhou X, Wang J, Yang B, Liu Y (2022)
Asperbenzophenone A and Versicolamide C, New Fungal Metabolites from the Soft Coral Derived Aspergillus sp. SCSIO 41036
Chem Biodivers
:e202100925
Long J, Pang X, Lin X, Liao S, Zhou X, Wang J, Yang B, Liu Y (2022)
Chem Biodivers
:e202100925