Title : The Lingula genome provides insights into brachiopod evolution and the origin of phosphate biomineralization - Luo_2015_Nat.Commun_6_8301 |
Author(s) : Luo YJ , Takeuchi T , Koyanagi R , Yamada L , Kanda M , Khalturina M , Fujie M , Yamasaki S , Endo K , Satoh N |
Ref : Nat Commun , 6 :8301 , 2015 |
Abstract :
The evolutionary origins of lingulid brachiopods and their calcium phosphate shells have been obscure. Here we decode the 425-Mb genome of Lingula anatina to gain insights into brachiopod evolution. Comprehensive phylogenomic analyses place Lingula close to molluscs, but distant from annelids. The Lingula gene number has increased to approximately 34,000 by extensive expansion of gene families. Although Lingula and vertebrates have superficially similar hard tissue components, our genomic, transcriptomic and proteomic analyses show that Lingula lacks genes involved in bone formation, indicating an independent origin of their phosphate biominerals. Several genes involved in Lingula shell formation are shared by molluscs. However, Lingula has independently undergone domain combinations to produce shell matrix collagens with EGF domains and carries lineage-specific shell matrix proteins. Gene family expansion, domain shuffling and co-option of genes appear to be the genomic background of Lingula's unique biomineralization. This Lingula genome provides resources for further studies of lophotrochozoan evolution. |
PubMedSearch : Luo_2015_Nat.Commun_6_8301 |
PubMedID: 26383154 |
Gene_locus related to this paper: linun-a0a1s3h3d9 , linun-a0a2r2mta8 |
Gene_locus | linun-a0a1s3h3d9 linun-a0a2r2mta8 |
Luo YJ, Takeuchi T, Koyanagi R, Yamada L, Kanda M, Khalturina M, Fujie M, Yamasaki S, Endo K, Satoh N (2015)
The Lingula genome provides insights into brachiopod evolution and the origin of phosphate biomineralization
Nat Commun
6 :8301
Luo YJ, Takeuchi T, Koyanagi R, Yamada L, Kanda M, Khalturina M, Fujie M, Yamasaki S, Endo K, Satoh N (2015)
Nat Commun
6 :8301