| Title : Acylphenols from Myristica crassa as new acetylcholinesterase inhibitors - Maia_2008_Planta.Med_74_1457 |
| Author(s) : Maia A , Schmitz-Afonso I , Martin MT , Awang K , Laprevote O , Gueritte F , Litaudon M |
| Ref : Planta Med , 74 :1457 , 2008 |
|
Abstract :
A significant acetylcholinesterase inhibitory activity was observed for the ethyl acetate and methanol extracts from the leaves and the fruits of MYRISTICA CRASSA. Three new dimeric acylphenols, giganteone C ( 5), maingayones B and C ( 6 and 7) were isolated together with the known malabaricones B and C ( 2 and 3) and giganteone A ( 4). Compounds 2 and 3 possess significant inhibitory activity on acetylcholinesterase. LC/MS study was particularly useful to discriminate structures of compounds 6 and 7. |
| PubMedSearch : Maia_2008_Planta.Med_74_1457 |
| PubMedID: 18671198 |
Maia A, Schmitz-Afonso I, Martin MT, Awang K, Laprevote O, Gueritte F, Litaudon M (2008)
Acylphenols from Myristica crassa as new acetylcholinesterase inhibitors
Planta Med
74 :1457
Maia A, Schmitz-Afonso I, Martin MT, Awang K, Laprevote O, Gueritte F, Litaudon M (2008)
Planta Med
74 :1457