| Title : Is the internal calcium regulation altered in type A botulinum toxin-poisoned motor endings? - Mallart_1989_Brain.Res_479_167 |
| Author(s) : Mallart A , Molgo J , Angaut-Petit D , Thesleff S |
| Ref : Brain Research , 479 :167 , 1989 |
|
Abstract :
The hypothesis according to which botulinum A toxin blocks acetylcholine release from motor endings by stimulating intracellular Ca2+ disposal systems was tested by recording presynaptic membrane currents from poisoned muscles. Calcium and calcium-activated potassium currents displayed amplitudes, time courses and stimulation frequency-dependent inactivation similar to those observed in unpoisoned preparations. This indicates that poisoned endings are no more efficient than normal ones in dealing with Ca2+ overloads. |
| PubMedSearch : Mallart_1989_Brain.Res_479_167 |
| PubMedID: 2538205 |
Mallart A, Molgo J, Angaut-Petit D, Thesleff S (1989)
Is the internal calcium regulation altered in type A botulinum toxin-poisoned motor endings?
Brain Research
479 :167
Mallart A, Molgo J, Angaut-Petit D, Thesleff S (1989)
Brain Research
479 :167