| Title : Draft Genome Sequence of Escherichia coli Strain VKPM B-10182, Producing the Enzyme for Synthesis of Cephalosporin Acids - Mardanov_2014_Genome.Announc_2_ |
| Author(s) : Mardanov AV , Eldarov MA , Sklyarenko AV , Dumina MV , Beletsky AV , Yarotsky SV , Ravin NV |
| Ref : Genome Announc , 2 : , 2014 |
|
Abstract :
Escherichia coli strain VKPM B-10182, obtained by chemical mutagenesis from E. coli strain ATCC 9637, produces cephalosporin acid synthetase employed in the synthesis of beta-lactam antibiotics, such as cefazolin. The draft genome sequence of strain VKPM B-10182 revealed 32 indels and 1,780 point mutations that might account for the improvement in antibiotic synthesis that we observed. |
| PubMedSearch : Mardanov_2014_Genome.Announc_2_ |
| PubMedID: 25414512 |
Mardanov AV, Eldarov MA, Sklyarenko AV, Dumina MV, Beletsky AV, Yarotsky SV, Ravin NV (2014)
Draft Genome Sequence of Escherichia coli Strain VKPM B-10182, Producing the Enzyme for Synthesis of Cephalosporin Acids
Genome Announc
2 :
Mardanov AV, Eldarov MA, Sklyarenko AV, Dumina MV, Beletsky AV, Yarotsky SV, Ravin NV (2014)
Genome Announc
2 :