| Title : Improved access to 2-O-monobenzyl ethers of beta-cyclodextrin as precursors of catalysts for organophosphoryl esters hydrolysis - Masurier_2006_Carbohydr.Res_341_935 |
| Author(s) : Masurier N , Estour F , Lefevre B , Brasme B , Masson P , Lafont O |
| Ref : Carbohydr Res , 341 :935 , 2006 |
|
Abstract :
A comparative study of reaction conditions was performed for the synthesis of a 2-O-monobenzyl ether of cyclomaltoheptaose (beta-CD). Optimal conditions involved sodium ethoxide in Me(2)SO and benzyl bromide. The methodology was extended to the preparation of various 2(I)-O-iodobenzyl and 2(I)-O-carboxymethylbenzyl derivatives of beta-CD including a 3-carboxymethyl-4-iodobenzyl derivative of interest as precursor of an enzyme mimic to degrade the organophosphoryl ester diethyl 4-nitrophenyl phosphate (paraoxon). |
| PubMedSearch : Masurier_2006_Carbohydr.Res_341_935 |
| PubMedID: 16530173 |
Masurier N, Estour F, Lefevre B, Brasme B, Masson P, Lafont O (2006)
Improved access to 2-O-monobenzyl ethers of beta-cyclodextrin as precursors of catalysts for organophosphoryl esters hydrolysis
Carbohydr Res
341 :935
Masurier N, Estour F, Lefevre B, Brasme B, Masson P, Lafont O (2006)
Carbohydr Res
341 :935