Title : Early life adversity in piglets induces long-term upregulation of the enteric cholinergic nervous system and heightened, sex-specific secretomotor neuron responses - Medland_2016_Neurogastroenterol.Motil_28_1317 |
Author(s) : Medland JE , Pohl CS , Edwards LL , Frandsen S , Bagley K , Li Y , Moeser AJ |
Ref : Neurogastroenterol Motil , 28 :1317 , 2016 |
Abstract :
BACKGROUND: Early life adversity (ELA) is a risk factor for the later-life onset of gastrointestinal (GI) diseases such as irritable bowel syndrome (IBS); however, the mechanisms are poorly understood. Here, we utilized a porcine model of ELA, early weaning stress (EWS), to investigate the influence of ELA on the development and function of the enteric nervous system (ENS). |
PubMedSearch : Medland_2016_Neurogastroenterol.Motil_28_1317 |
PubMedID: 27134125 |
Medland JE, Pohl CS, Edwards LL, Frandsen S, Bagley K, Li Y, Moeser AJ (2016)
Early life adversity in piglets induces long-term upregulation of the enteric cholinergic nervous system and heightened, sex-specific secretomotor neuron responses
Neurogastroenterol Motil
28 :1317
Medland JE, Pohl CS, Edwards LL, Frandsen S, Bagley K, Li Y, Moeser AJ (2016)
Neurogastroenterol Motil
28 :1317