| Title : Acetylcholinesterase and butyrylcholinesterase inhibition of ethanolic extract and monoterpenes from Pimpinella anisoides V Brig. (Apiaceae) - Menichini_2009_Fitoterapia_80_297 |
| Author(s) : Menichini F , Tundis R , Loizzo MR , Bonesi M , Marrelli M , Statti GA , Conforti F |
| Ref : Fitoterapia , 80 :297 , 2009 |
|
Abstract :
Ethanolic extract from the fruits of Pimpinella anisoides, an aromatic plant and a spice, exhibited activity against AChE and BChE, with IC(50) values of 227.5 and 362.1 microg/ml, respectively. The most abundant constituents of the extract were trans-anethole, (+)-limonene and (+)-sabinene. trans-Anethole exhibited the highest activity against AChE and BChE with IC(50) values of 134.7 and 209.6 microg/ml, respectively. The bicyclic monoterpene (+)-sabinene exhibited a promising activity against AChE (IC(50) of 176.5 microg/ml) and BChE (IC(50) of 218.6 microg/ml). |
| PubMedSearch : Menichini_2009_Fitoterapia_80_297 |
| PubMedID: 19351555 |
Menichini F, Tundis R, Loizzo MR, Bonesi M, Marrelli M, Statti GA, Conforti F (2009)
Acetylcholinesterase and butyrylcholinesterase inhibition of ethanolic extract and monoterpenes from Pimpinella anisoides V Brig. (Apiaceae)
Fitoterapia
80 :297
Menichini F, Tundis R, Loizzo MR, Bonesi M, Marrelli M, Statti GA, Conforti F (2009)
Fitoterapia
80 :297