Merga_2013_PLoS.One_8_e55240

Reference

Title : Exploring the diversity of Arcobacter butzleri from cattle in the UK using MLST and whole genome sequencing - Merga_2013_PLoS.One_8_e55240
Author(s) : Merga JY , Williams NJ , Miller WG , Leatherbarrow AJ , Bennett M , Hall N , Ashelford KE , Winstanley C
Ref : PLoS ONE , 8 :e55240 , 2013
Abstract :

Arcobacter butzleri is considered to be an emerging human foodborne pathogen. The completion of an A. butzleri genome sequence along with microarray analysis of 13 isolates in 2007 revealed a surprising amount of diversity amongst A. butzleri isolates from humans, animals and food. In order to further investigate Arcobacter diversity, 792 faecal samples were collected from cattle on beef and dairy farms in the North West of England. Arcobacter was isolated from 42.5% of the samples and the diversity of the isolates was investigated using multilocus sequence typing. An A. butzleri whole genome sequence, obtained by 454 shotgun sequencing of an isolate from a clinically-healthy dairy cow, showed a number of differences when compared to the genome of a human-derived A. butzleri isolate. PCR-based prevalence assays for variable genes suggested some tentative evidence for source-related distributions. We also found evidence for phenotypic differences relating to growth capabilities between our representative human and cattle isolates. Our genotypic and phenotypic observations suggest that some level of niche adaptation may have occurred in A. butzleri.

PubMedSearch : Merga_2013_PLoS.One_8_e55240
PubMedID: 23405126
Gene_locus related to this paper: 9prot-e6l4v2 , 9prot-a0a0g9kwp1

Related information

Gene_locus 9prot-e6l4v2    9prot-a0a0g9kwp1

Citations formats

Merga JY, Williams NJ, Miller WG, Leatherbarrow AJ, Bennett M, Hall N, Ashelford KE, Winstanley C (2013)
Exploring the diversity of Arcobacter butzleri from cattle in the UK using MLST and whole genome sequencing
PLoS ONE 8 :e55240

Merga JY, Williams NJ, Miller WG, Leatherbarrow AJ, Bennett M, Hall N, Ashelford KE, Winstanley C (2013)
PLoS ONE 8 :e55240