| Title : Effect of quinolinic acid in the nucleus basalis magnocellularis on cortical high-affinity choline uptake - Metcalf_1987_J.Neurochem_49_639 |
| Author(s) : Metcalf RH , Boegman RJ , Quirion R , Riopelle RJ , Ludwin SK |
| Ref : Journal of Neurochemistry , 49 :639 , 1987 |
|
Abstract :
A transient 45% increase in cortical high-affinity choline uptake (HACU) was observed after an injection of quinolinic acid (QUIN) into the nucleus basalis magnocellularis (nbM) of the rat. This was followed by a steady decline in choline uptake, which resulted in a 46% decrease by day 7. Specific [3H]hemicholinium-3 binding to coronal brain sections showed a similar pattern following injections of QUIN into the nbM. The increase in cortical HACU elicited by QUIN appeared to be dose dependent. |
| PubMedSearch : Metcalf_1987_J.Neurochem_49_639 |
| PubMedID: 2955081 |
Metcalf RH, Boegman RJ, Quirion R, Riopelle RJ, Ludwin SK (1987)
Effect of quinolinic acid in the nucleus basalis magnocellularis on cortical high-affinity choline uptake
Journal of Neurochemistry
49 :639
Metcalf RH, Boegman RJ, Quirion R, Riopelle RJ, Ludwin SK (1987)
Journal of Neurochemistry
49 :639