Michaelson_1980_J.Physiol.Paris_76_505

Reference

Title : On the regulation of acetylcholine release: a study utilizing Torpedo synaptosomes and synaptic vesicles - Michaelson_1980_J.Physiol.Paris_76_505
Author(s) : Michaelson DM , Avissar S , Ophir I , Pinchasi I , Angel I , Kloog Y , Sokolovsky M
Ref : Journal de Physiologie (Paris) , 76 :505 , 1980
Abstract :

1. Addition of ATP to isolated highly purified Torpedo synaptic vesicles results in 45Ca2+ uptake. 2. Ca2+ dependent ACh release from Torpedo synaptosomes is accompanied by the phosphorylation of a specific protein with an apparent subunit molecular weight of about 100,000 (band alpha). 3. Activation of the presynaptic muscarinic receptors by an agonist inhibits Ca2+-dependent ACh release from Torpedo synaptosomes. This process seems to be mediated through an interference with the phosphorylation of the band alpha protein, and not by blocking the voltage-dependent presynaptic Ca2+ channel.

PubMedSearch : Michaelson_1980_J.Physiol.Paris_76_505
PubMedID: 7452519

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Citations formats

Michaelson DM, Avissar S, Ophir I, Pinchasi I, Angel I, Kloog Y, Sokolovsky M (1980)
On the regulation of acetylcholine release: a study utilizing Torpedo synaptosomes and synaptic vesicles
Journal de Physiologie (Paris) 76 :505

Michaelson DM, Avissar S, Ophir I, Pinchasi I, Angel I, Kloog Y, Sokolovsky M (1980)
Journal de Physiologie (Paris) 76 :505