| Title : Partition coefficients of selected pyridine carbamates and comparisons with their acetylcholinesterase and butyrylcholinesterase inhibitory potencies - Millner_1976_J.Pharm.Sci_65_910 |
| Author(s) : Millner OE, Jr. , Purcell WP |
| Ref : J Pharm Sci , 65 :910 , 1976 |
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Abstract :
Partition coefficients of a series of 2-substituted 3-(N,N-dimethyl)carbamyloxypyridines were determined in an octanol-buffer (pH 7.4) system. The values obtained were compared with the ihnibitory potencies of acetylcholinesterase and butyrylcholinesterase. No significant difference was found for the role of hydrophobicity in the two enzyme systems. |
| PubMedSearch : Millner_1976_J.Pharm.Sci_65_910 |
| PubMedID: 932979 |
Millner OE, Jr., Purcell WP (1976)
Partition coefficients of selected pyridine carbamates and comparisons with their acetylcholinesterase and butyrylcholinesterase inhibitory potencies
J Pharm Sci
65 :910
Millner OE, Jr., Purcell WP (1976)
J Pharm Sci
65 :910