Mitchelson_1999_Proc.West.Pharmacol.Soc_42_109

Reference

Title : Studies on muscarinic M2 receptors in smooth muscle - Mitchelson_1999_Proc.West.Pharmacol.Soc_42_109
Author(s) : Mitchelson F , Shen A
Ref : Proc West Pharmacol Soc , 42 :109 , 1999
Abstract :

Histamine after M3 receptor alkylation with 4-DAMP mustard does not serve simply as a spasmogen but facilitates visualization of the M2-mediated contraction induced by oxotremorine M. We speculate that M3 receptor activation has a similar role in untreated tissue. The facilitation appears to involve protein kinase C. The results with propranolol suggest that the phospholipase D pathway may also be important in the development of the M2-mediated response.

PubMedSearch : Mitchelson_1999_Proc.West.Pharmacol.Soc_42_109
PubMedID: 10697708

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Citations formats

Mitchelson F, Shen A (1999)
Studies on muscarinic M2 receptors in smooth muscle
Proc West Pharmacol Soc 42 :109

Mitchelson F, Shen A (1999)
Proc West Pharmacol Soc 42 :109