| Title : [Pharmacological vigilance and pharmacological epidemiology: principles, definition, methods and current trends in neurology] - Montastruc_1999_Rev.Neurol.(Paris)_155_312 |
| Author(s) : Montastruc JL , Bagheri H , Lapeyre-Mestre M , Senard JM |
| Ref : Rev Neurol (Paris) , 155 :312 , 1999 |
|
Abstract :
It is now well established that only clinical trials performed before drug approval are not sufficient for a full modern pharmacological evaluation of drugs and treatments. The need of both pharmacovigilance and pharmacoepidemiology is underlined in order to evaluate drugs under real conditions. After a summary of methods used in pharmacoepidemiological trials (spontaneous reports, imputability assessment, cohorts, case control studies etc.), recent pharmacoepidemiological data useful for the neurologist are summarized: side effects of tacrine and vaccines, serotoninergic syndrome and side effects of new antiepileptic drugs. |
| PubMedSearch : Montastruc_1999_Rev.Neurol.(Paris)_155_312 |
| PubMedID: 10367330 |
Montastruc JL, Bagheri H, Lapeyre-Mestre M, Senard JM (1999)
[Pharmacological vigilance and pharmacological epidemiology: principles, definition, methods and current trends in neurology]
Rev Neurol (Paris)
155 :312
Montastruc JL, Bagheri H, Lapeyre-Mestre M, Senard JM (1999)
Rev Neurol (Paris)
155 :312