Muley_2014_Indian.J.Crit.Care.Med_18_297

BACKGROUND: Organophosphorus poisoning remains an important cause of morbidity and mortality, but no definite parameters have been identified as predictors of outcome. Prediction of morbidity at presentation might help in decision making in places of limited resources like rural settings in developing countries. MATERIALS AND
METHODS: A total of 76 cases were included in this retrospective cohort study. Logged relative risk of requirement of mechanical ventilation and hospital stay >7 days was measured in patients with serum acetylcholinesterase (s. acetylcholinesterase) <1000 versus >1000, presenting in <2 h versus >/= 2 h after exposure, with Glasgow Coma Scale (GCS) RESULTS: S. acetylcholinesterase <1000, time elapsed after ingestion to presentation >/= 2 h and SpO2 (at room air) at presentation <85% were found to have positive association with requirement of ventilation. GCS