Nabeshima_2003_Biochem.Biophys.Res.Commun_307_15

Reference

Title : An amino acid substitution on the second acetylcholinesterase in the pirimicarb-resistant strains of the peach potato aphid, Myzus persicae - Nabeshima_2003_Biochem.Biophys.Res.Commun_307_15
Author(s) : Nabeshima T , Kozaki T , Tomita T , Kono Y
Ref : Biochemical & Biophysical Research Communications , 307 :15 , 2003
Abstract :

cDNAs encoding two acetylcholinesterases (AChEs) were isolated from the peach potato aphid, Myzus persicae. MpAChE1 was orthologous and MpAChE2 was paralogous with the ace of Drosophila melanogaster. The deduced amino acid sequence of MpAChE1 cDNA was identical between the pirimicarb susceptible and resistant strains. However, a single amino acid substitution of Ser431Phe on MpAchE2 was found in the pirimicarb resistant strains. This substitution was located in the acyl pocket of the enzyme and was thought to alter the ligand specificity.

PubMedSearch : Nabeshima_2003_Biochem.Biophys.Res.Commun_307_15
PubMedID: 12849975
Gene_locus related to this paper: myzpe-ACHE , myzpe-ACHEm

Related information

Mutation S431F_myzpe-ACHEm
Gene_locus S431F_myzpe-ACHEm    myzpe-ACHE    myzpe-ACHEm

Citations formats

Nabeshima T, Kozaki T, Tomita T, Kono Y (2003)
An amino acid substitution on the second acetylcholinesterase in the pirimicarb-resistant strains of the peach potato aphid, Myzus persicae
Biochemical & Biophysical Research Communications 307 :15

Nabeshima T, Kozaki T, Tomita T, Kono Y (2003)
Biochemical & Biophysical Research Communications 307 :15