| Title : Depsitinuside: a new depside galactoside from an endophytic fungus isolated from Viburnum tinus - Nazir_2011_J.Asian.Nat.Prod.Res_13_1056 |
| Author(s) : Nazir M , Sultan M , Riaz N , Hafeez M , Hussain H , Ahmed I , Schulz B , Draeger S , Jabbar A , Krohn K , Ashraf M , Saleem M |
| Ref : J Asian Nat Prod Res , 13 :1056 , 2011 |
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Abstract :
Chromatographic purification of the extract of an endophytic fungal culture yielded depsitinuside (1), a new phenolic ester together with ergosterol (2) and (22E,24S)-24-methyl-5-alpha-cholesta-7,22-diene-3beta,5,6beta-triol (3). The structure of 1 was elucidated based on 1D, 2D NMR spectroscopy and high-resolution mass spectrometry, whereas the known compounds (2 and 3) were identified by (1)H NMR, mass spectrometry, and in comparison with the literature values. Compound 1 was evaluated for its enzyme inhibitory potential against acetylcholinesterase, butyrylcholinesterase and lipoxygenase, and was found inactive (10%-40% inhibition at a concentration of 2 mg/ml). |
| PubMedSearch : Nazir_2011_J.Asian.Nat.Prod.Res_13_1056 |
| PubMedID: 21985077 |
Nazir M, Sultan M, Riaz N, Hafeez M, Hussain H, Ahmed I, Schulz B, Draeger S, Jabbar A, Krohn K, Ashraf M, Saleem M (2011)
Depsitinuside: a new depside galactoside from an endophytic fungus isolated from Viburnum tinus
J Asian Nat Prod Res
13 :1056
Nazir M, Sultan M, Riaz N, Hafeez M, Hussain H, Ahmed I, Schulz B, Draeger S, Jabbar A, Krohn K, Ashraf M, Saleem M (2011)
J Asian Nat Prod Res
13 :1056