| Title : The effect of banol and paraoxon on the NADPH-cytochrome c reductase activity and cytochrome P-450 content in rats - Neskovic_1977_Bull.Environ.Contam.Toxicol_18_472 |
| Author(s) : Neskovic NK , Vitorovic SL |
| Ref : Bulletin of Environmental Contamination & Toxicology , 18 :472 , 1977 |
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Abstract :
We investigated the effect of banol and paraoxon on the activity of NADPH-cytochrome c reductase and cytochrome P-450 concentration in microsomes of rats treated in vivo with these compounds alone, or in the presence of phenobarbitone. The results showed that banol reduced the NADPH-cytochrome c reductase activity and the concentration of cytochrome P-450, while paraoxon reduced the activity of NADPH-cytochrome c reductase, but increased the cytochrome P-450 concentration. Phenobarbitone stimulated an increased NADPH-cytochrome c reductase activity and cytochrome P-450 concentration. When applied with banol and paraoxon, phenobarbitone lowered their inhibitory effect. |
| PubMedSearch : Neskovic_1977_Bull.Environ.Contam.Toxicol_18_472 |
| PubMedID: 411532 |
Neskovic NK, Vitorovic SL (1977)
The effect of banol and paraoxon on the NADPH-cytochrome c reductase activity and cytochrome P-450 content in rats
Bulletin of Environmental Contamination & Toxicology
18 :472
Neskovic NK, Vitorovic SL (1977)
Bulletin of Environmental Contamination & Toxicology
18 :472