Ngowi_2025_Case.Rep.Ophthalmol_16_454

Reference

Title : Juvenile Ocular Myasthenia Gravis in a 3-Year-Old African Girl: A Case Report - Ngowi_2025_Case.Rep.Ophthalmol_16_454
Author(s) : Ngowi E , Lusheke H , Mbuma R , Juneja Z , Mbuki M , Thaver SP , Magodi T , Osman R , Salum H
Ref : Case Rep Ophthalmol , 16 :454 , 2025
Abstract :

INTRODUCTION: Myasthenia gravis (MG) is an autoimmune disorder causing muscle weakness. When diagnosed before 18, it is termed juvenile MG. Ocular symptoms are more common in children than adults. Diagnosis of ocular MG involves tests like the ice pack test, while treatment includes cholinesterase inhibitors and corticosteroids. CASE PRESENTATION: We present a case of a 3-year-old girl who had a 2-month history of progressive weakness of both eyelids, but no other body weakness reported. She was diagnosed with ocular MG after a positive ice pack test and detection of autoantibodies against acetylcholine receptors. She was started on pyridostigmine and later added cyclosporine, and her symptoms improved greatly afterward. CONCLUSION: Ocular MG is rare. This case report highlights the challenges of diagnosing and managing ocular MG in low-resource settings, stressing the need for early recognition and treatment.

PubMedSearch : Ngowi_2025_Case.Rep.Ophthalmol_16_454
PubMedID: 40551857

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Citations formats

Ngowi E, Lusheke H, Mbuma R, Juneja Z, Mbuki M, Thaver SP, Magodi T, Osman R, Salum H (2025)
Juvenile Ocular Myasthenia Gravis in a 3-Year-Old African Girl: A Case Report
Case Rep Ophthalmol 16 :454

Ngowi E, Lusheke H, Mbuma R, Juneja Z, Mbuki M, Thaver SP, Magodi T, Osman R, Salum H (2025)
Case Rep Ophthalmol 16 :454