Oe_2021_Chem.Commun.(Camb)__

Reference

Title : An activator-induced quencher-detachment-based turn-on probe with a cationic substrate moiety for acetylcholinesterase - Oe_2021_Chem.Commun.(Camb)__
Author(s) : Oe M , Miki K , Masuda A , Nogita K , Ohe K
Ref : Chem Commun (Camb) , : , 2021
Abstract :

We report a choline ester-grafted turn-on fluorescence probe to detect acetylcholinesterase (AChE) in living cells. The AChE-mediated hydrolysis of the choline ester moiety producing carboxylate initiates the activation of the Cy5 fluorophore quenched by an intramolecular nucleophilic mercapto group. The probe has the advantages of high AChE affinity and low cytotoxicity.

PubMedSearch : Oe_2021_Chem.Commun.(Camb)__
PubMedID: 34874369

Related information

Citations formats

Oe M, Miki K, Masuda A, Nogita K, Ohe K (2021)
An activator-induced quencher-detachment-based turn-on probe with a cationic substrate moiety for acetylcholinesterase
Chem Commun (Camb) :

Oe M, Miki K, Masuda A, Nogita K, Ohe K (2021)
Chem Commun (Camb) :