Patil_2003_Indian.J.Clin.Biochem_18_16

A total of 85 healthy male pesticide sprayers in grape garden exposed to different class of pesticides for 3 to 10 years were compared with 75 controls matched for age with respect to serum cholinesterase serum total protein albumin AST ALT hematological parameters such as Hb Hct RBC and serum lipid peroxidation Serum lipid peroxidation was estimated in the form of thiobarbituric acid reactive substances TBARS produced Significant decrease was observed in serum cholinesterase serum total proteins albumin and hematological parameters viz Hb Hct and RBC Significant increase in lipid peroxidation AST ALT was observed in exposed group when compared with control These results suggest that the long term exposure of various pesticides on sprayers of grape garden affect liver heme biosynthesis and decrease serum cholinesterase.