| Title : Neural substrate of nicotine addiction as defined by functional brain maps of gene expression - Pich_1998_J.Physiol.Paris_92_225 |
| Author(s) : Pich EM , Chiamulera C , Tessari M |
| Ref : Journal de Physiologie (Paris) , 92 :225 , 1998 |
|
Abstract :
The distributed neural networks involved in the intravenous self-administration of nicotine and cocaine, and in a model of relapse of nicotine-taking after abstinence, were compared in Wistar rats. Post-mortem brain maps of c-fos-related antigens expression showed specific activation in prefrontal cortex, anterior cingulate and nucleus accumbens for both drugs, but of the anterior cingulate cortex only during relapse, suggesting that a subset of the neural network involved in drug self-administration is activated during relapse. |
| PubMedSearch : Pich_1998_J.Physiol.Paris_92_225 |
| PubMedID: 9789813 |
Pich EM, Chiamulera C, Tessari M (1998)
Neural substrate of nicotine addiction as defined by functional brain maps of gene expression
Journal de Physiologie (Paris)
92 :225
Pich EM, Chiamulera C, Tessari M (1998)
Journal de Physiologie (Paris)
92 :225