Plant_1996_Pest.Sci_48_351

Reference

Title : Synthesis and Anthelmintic Activity of 7-Hydroxy- 5-oxo-5H-thieno[3,2-b]pyran-6-carboxanilides and -6-thiocarboxanilides - Plant_1996_Pest.Sci_48_351
Author(s) : Plant A , Harder A , Mencke N , Bertram H-J
Ref : Pest Sci , 48 :351 , 1996
Abstract :

7-Hydroxy-5-oxo-5H-thieno[3,2-b]pyran-6-carboxanilides and -6-thio-carboxanilides represent a novel series of anthelmintic compounds, with broad-spectrum activity against important parasitic nematodes in sheep and dogs. In particular, an improved efficacy against Trichostrongylus colubriformis in sheep over the related 3-carbamoyl-4-hydroxycoumarins has been noted. New synthetic routes to the key intermediate, 7-hydroxythieno[3,2-b]pyran-5-one, have been developed.

PubMedSearch : Plant_1996_Pest.Sci_48_351
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Citations formats

Plant A, Harder A, Mencke N, Bertram H-J (1996)
Synthesis and Anthelmintic Activity of 7-Hydroxy- 5-oxo-5H-thieno[3,2-b]pyran-6-carboxanilides and -6-thiocarboxanilides
Pest Sci 48 :351

Plant A, Harder A, Mencke N, Bertram H-J (1996)
Pest Sci 48 :351