Title : Synthesis and Anthelmintic Activity of 7-Hydroxy- 5-oxo-5H-thieno[3,2-b]pyran-6-carboxanilides and -6-thiocarboxanilides - Plant_1996_Pest.Sci_48_351 |
Author(s) : Plant A , Harder A , Mencke N , Bertram H-J |
Ref : Pest Sci , 48 :351 , 1996 |
Abstract :
7-Hydroxy-5-oxo-5H-thieno[3,2-b]pyran-6-carboxanilides and -6-thio-carboxanilides represent a novel series of anthelmintic compounds, with broad-spectrum activity against important parasitic nematodes in sheep and dogs. In particular, an improved efficacy against Trichostrongylus colubriformis in sheep over the related 3-carbamoyl-4-hydroxycoumarins has been noted. New synthetic routes to the key intermediate, 7-hydroxythieno[3,2-b]pyran-5-one, have been developed. |
PubMedSearch : Plant_1996_Pest.Sci_48_351 |
PubMedID: |
Plant A, Harder A, Mencke N, Bertram H-J (1996)
Synthesis and Anthelmintic Activity of 7-Hydroxy- 5-oxo-5H-thieno[3,2-b]pyran-6-carboxanilides and -6-thiocarboxanilides
Pest Sci
48 :351
Plant A, Harder A, Mencke N, Bertram H-J (1996)
Pest Sci
48 :351