Polinski_2021_Sci.Adv_7_eabe8290

Reference

Title : The American lobster genome reveals insights on longevity, neural, and immune adaptations - Polinski_2021_Sci.Adv_7_eabe8290
Author(s) : Polinski JM , Zimin AV , Clark KF , Kohn AB , Sadowski N , Timp W , Ptitsyn A , Khanna P , Romanova DY , Williams P , Greenwood SJ , Moroz LL , Walt DR , Bodnar AG
Ref : Sci Adv , 7 : , 2021
Abstract :

The American lobster, Homarus americanus, is integral to marine ecosystems and supports an important commercial fishery. This iconic species also serves as a valuable model for deciphering neural networks controlling rhythmic motor patterns and olfaction. Here, we report a high-quality draft assembly of the H. americanus genome with 25,284 predicted gene models. Analysis of the neural gene complement revealed extraordinary development of the chemosensory machinery, including a profound diversification of ligand-gated ion channels and secretory molecules. The discovery of a novel class of chimeric receptors coupling pattern recognition and neurotransmitter binding suggests a deep integration between the neural and immune systems. A robust repertoire of genes involved in innate immunity, genome stability, cell survival, chemical defense, and cuticle formation represents a diversity of defense mechanisms essential to thrive in the benthic marine environment. Together, these unique evolutionary adaptations contribute to the longevity and ecological success of this long-lived benthic predator.

PubMedSearch : Polinski_2021_Sci.Adv_7_eabe8290
PubMedID: 34162536
Gene_locus related to this paper: homam-a0a8j5mne5

Related information

Gene_locus homam-a0a8j5mne5

Citations formats

Polinski JM, Zimin AV, Clark KF, Kohn AB, Sadowski N, Timp W, Ptitsyn A, Khanna P, Romanova DY, Williams P, Greenwood SJ, Moroz LL, Walt DR, Bodnar AG (2021)
The American lobster genome reveals insights on longevity, neural, and immune adaptations
Sci Adv 7 :

Polinski JM, Zimin AV, Clark KF, Kohn AB, Sadowski N, Timp W, Ptitsyn A, Khanna P, Romanova DY, Williams P, Greenwood SJ, Moroz LL, Walt DR, Bodnar AG (2021)
Sci Adv 7 :