| Title : [Ganglionic synapses of Aplysia as a model for the study of the mechanism of action of botulinum neurotoxins] - Poulain_1988_C.R.Acad.Sci.III_306_483 |
| Author(s) : Poulain B , Tauc L , Maisey EA , Dolly JO |
| Ref : Comptes Rendus de l Academie des Sciences , 306 :483 , 1988 |
|
Abstract :
The action of type A and type B botulinum neurotoxin on neurotransmitter release was studied on identified ganglionic synapses of Aplysia. Using this model, we have shown that botulinum neurotoxins at concentrations used in vertebrate preparations had the same specificity of action and that both heavy and light chains of these toxins are intracellularly required to inhibit neurotransmitter release. |
| PubMedSearch : Poulain_1988_C.R.Acad.Sci.III_306_483 |
| PubMedID: 2900674 |
Poulain B, Tauc L, Maisey EA, Dolly JO (1988)
[Ganglionic synapses of Aplysia as a model for the study of the mechanism of action of botulinum neurotoxins]
Comptes Rendus de l Academie des Sciences
306 :483
Poulain B, Tauc L, Maisey EA, Dolly JO (1988)
Comptes Rendus de l Academie des Sciences
306 :483