| Title : Evaluation of anti-cholinesterase, antibacterial and cytotoxic activities of green synthesized silver nanoparticles using from Millettia pinnata flower extract - Rajakumar_2016_Microb.Pathog_103_123 |
| Author(s) : Rajakumar G , Gomathi T , Thiruvengadam M , Devi Rajeswari V , Kalpana VN , Chung IM |
| Ref : Microb Pathog , 103 :123 , 2016 |
|
Abstract :
The aim of this study is to develop an easy and eco-friendly method for the synthesis of Ag-NPs using extracts from the medicinal plant, Millettia pinnata flower extract and investigate the effects of Ag-NPs on acetylcholinesterase (AChE), butyrylcholinesterase (BChE), antibacterial and cytotoxicity activity. UV-Vis peak at 438 nm confirmed the Ag-NPs absorbance. The SEM analysis results confirmed the presence of spherical shaped Ag-NPs by a huge disparity in the particle size distribution with an average size of 49 +/- 0.9 nm. TEM images revealed the formation of Ag-NPs with spherical shape and sizes in the range between 16 and 38 nm. The Ag-NPs showed an excellent inhibitory efficacy against AChE and BChE. The highest antibacterial activity was found against Escherichia coli (20.25 +/- 0.91 mm). These nanoparticles showed the cytotoxic effects against brine shrimp (artemia saliana) nauplii with a LD50 value of 33.92. |
| PubMedSearch : Rajakumar_2016_Microb.Pathog_103_123 |
| PubMedID: 28025099 |
Rajakumar G, Gomathi T, Thiruvengadam M, Devi Rajeswari V, Kalpana VN, Chung IM (2016)
Evaluation of anti-cholinesterase, antibacterial and cytotoxic activities of green synthesized silver nanoparticles using from Millettia pinnata flower extract
Microb Pathog
103 :123
Rajakumar G, Gomathi T, Thiruvengadam M, Devi Rajeswari V, Kalpana VN, Chung IM (2016)
Microb Pathog
103 :123