Rajini_1985_Int.J.Vitam.Nutr.Res_55_421

Reference

Title : Effect of L-ascorbic acid supplementation on the toxicity of pirimiphos- methyl to albino rats - Rajini_1985_Int.J.Vitam.Nutr.Res_55_421
Author(s) : Rajini PS , Krishnakumari MK
Ref : Int J Vitam Nutr Res , 55 :421 , 1985
Abstract :

The effect of L-ascorbic acid supplementation on Pirimiphos-methyl induced toxicity was studied in albino rats. Biochemical estimations were made in rats administered orally the insecticide at 100 and 200 mg/kg body weight with or without oral supplementation of L-ascorbic acid at 200 mg/kg b.w. The biochemical assessments included estimations of brain and plasma cholinesterases, levels of ascorbic acid in liver, kidney and adrenals, urinary levels of ascorbic acid and glucuronic acid. A lower degree of inhibition of the cholinesterases were evident in ascorbic acid supplemented rats. Marked elevation in urinary levels of ascorbic acid and glucuronic acid was observed in the insecticide treated rats. Results of this study suggests that L-ascorbic acid supplementation partially offsets Pirimiphos-methyl induced toxicity.

PubMedSearch : Rajini_1985_Int.J.Vitam.Nutr.Res_55_421
PubMedID: 4086212

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Citations formats

Rajini PS, Krishnakumari MK (1985)
Effect of L-ascorbic acid supplementation on the toxicity of pirimiphos- methyl to albino rats
Int J Vitam Nutr Res 55 :421

Rajini PS, Krishnakumari MK (1985)
Int J Vitam Nutr Res 55 :421