Rajini_1989_J.Environ.Sci.Health.[B]_24_509

Reference

Title : Inhibitory pattern of tissue esterases in rats fed dietary pirimiphos- methyl - Rajini_1989_J.Environ.Sci.Health.[B]_24_509
Author(s) : Rajini PS , Muralidhara , Krishnakumari MK
Ref : J Environ Sci Health [B] , 24 :509 , 1989
Abstract :

Activities of Acetylcholinesterase (AChE) in brain and erythrocytes, pseudocholinesterase (PChE) in plasma and non-specific carboxylesterase (NSE) in brain, liver, plasma and kidney were assayed at weekly intervals in growing male rats fed dietary pirimiphos-methyl at dosages of 1000, and 1500 ppm for a period of 28 days. Significant inhibition of tissue esterases were observed at the end of 7 days at both the dosages and the enzyme activities remained markedly inhibited at subsequent intervals. Activities of all enzymes (excepting Brain AChE) returned to normal levels following a 7-day maintenance on the insecticide-free diet implicating that pirimiphos-methyl induced little or no permanent tissue damage. The results suggest that plasma NSE level may also serve as a sensitive indicator in monitoring OPI exposure.

PubMedSearch : Rajini_1989_J.Environ.Sci.Health.[B]_24_509
PubMedID: 2600363

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Citations formats

Rajini PS, Muralidhara, Krishnakumari MK (1989)
Inhibitory pattern of tissue esterases in rats fed dietary pirimiphos- methyl
J Environ Sci Health [B] 24 :509

Rajini PS, Muralidhara, Krishnakumari MK (1989)
J Environ Sci Health [B] 24 :509