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Rathmann_2016_In.Vivo_30_707

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Title : Benefit of Patients with an Early and Progressed State of Hepatocellular Carcinoma Treated with Drug-eluting Beads - Rathmann_2016_In.Vivo_30_707
Author(s) : Rathmann N , Sadick M , Rathmann B , Kostrzewa M , Weiss C , Schoenberg SO , Diehl SJ , Antoni C
Ref : In Vivo , 30 :707 , 2016
Abstract :

AIM: To evaluate drug-eluting beads (DEB) for transarterial chemoembolization (TACE) in patients with Barcelona Clinic Liver Cancer (BCLC) A to D suffering from hepatocellular carcinoma. MATERIAL AND
METHODS: The progression-free interval (PFI), survival and laboratory findings of 46 patients were retrospectively analyzed after DEB TACE.
RESULTS: The mean survival interval was 16.93 months. The BCLC A/B group had significantly (p=0.01) longer survival compared to C/D: 20.44 and 10.36 months. Mean PFI was 10.75 months with a significantly (p=0.002) longer PFI of the BCLC A/B group (12.71 months) compared to BCLC C/D (3.91 months). In terms of possible adverse events (AEs) significant changes (p<0.05) were observed in cholinesterase, white blood cells, alkaline phosphatase and C-reactive protein. CONCLUSION: Mean survival and PFI results in the BCLC A/B patient group were comparable to historical controls. In addition, the results suggest that patients with BCLC stage C/D also benefited from DEB TACE.
PubMedSearch : Rathmann_2016_In.Vivo_30_707
PubMedID: 27566095

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Citations formats

Rathmann N, Sadick M, Rathmann B, Kostrzewa M, Weiss C, Schoenberg SO, Diehl SJ, Antoni C (2016)
Benefit of Patients with an Early and Progressed State of Hepatocellular Carcinoma Treated with Drug-eluting Beads
In Vivo 30 :707

Rathmann N, Sadick M, Rathmann B, Kostrzewa M, Weiss C, Schoenberg SO, Diehl SJ, Antoni C (2016)
In Vivo 30 :707