| Title : The pharmacological assessment of a new, potent oxotremorine analogue in mice and rats - Resul_1982_Eur.J.Pharmacol_80_209 |
| Author(s) : Resul B , Lewander T , Ringdahl B , Zetterstrom T , Dahlbom R |
| Ref : European Journal of Pharmacology , 80 :209 , 1982 |
|
Abstract :
Some of the central and peripheral effects of oxotremorine (OT) and its azetidine analogue, N-[4-azetidinyl)-2-butynyl]-2-pyrrolidone (BM 120), were compared in mice and rats. BM 120 was found to be about twice as potent as OT and to have a somewhat longer duration of action. All its effects were antagonized by pretreatment with atropine sulphate. BM 120 acted as powerful muscarinic agonist on the isolated guinea pig ileum. |
| PubMedSearch : Resul_1982_Eur.J.Pharmacol_80_209 |
| PubMedID: 7106176 |
Resul B, Lewander T, Ringdahl B, Zetterstrom T, Dahlbom R (1982)
The pharmacological assessment of a new, potent oxotremorine analogue in mice and rats
European Journal of Pharmacology
80 :209
Resul B, Lewander T, Ringdahl B, Zetterstrom T, Dahlbom R (1982)
European Journal of Pharmacology
80 :209