| Title : Excitotoxicity and cholinergic chemical markers during programmed motor neurone death - Rodriguez-Ithurralde_1994_J.Neurol.Sci_124_52 |
| Author(s) : Rodriguez-Ithurralde D , Vincent O |
| Ref : Journal of the Neurological Sciences , 124 :52 , 1994 |
|
Abstract :
We measured cholinergic markers and acetylcholinesterase (AChE) molecular forms after glutamate receptor stimulation of superfused slices of mouse spinal cord at different developmental ages. AChE globular forms were secreted in a dose-dependent fashion. A period of selective sensitivity to excitotoxic agents was detected by increased acetylcholine (ACh) release and AChE secretion (sAChE) at postnatal day 14. Strychnine-resistant glycine stimulation potentiated glutamate-induced AChE release, suggesting N-methyl-D-aspartate (NMDA) receptor involvement. |
| PubMedSearch : Rodriguez-Ithurralde_1994_J.Neurol.Sci_124_52 |
| PubMedID: 7807141 |
Rodriguez-Ithurralde D, Vincent O (1994)
Excitotoxicity and cholinergic chemical markers during programmed motor neurone death
Journal of the Neurological Sciences
124 :52
Rodriguez-Ithurralde D, Vincent O (1994)
Journal of the Neurological Sciences
124 :52