Title : An alpha\/beta-fold C--C bond hydrolase is involved in a central step of nicotine catabolism by Arthrobacter nicotinovorans - Sachelaru_2005_J.Bacteriol_187_8516 |
Author(s) : Sachelaru P , Schiltz E , Igloi GL , Brandsch R |
Ref : Journal of Bacteriology , 187 :8516 , 2005 |
Abstract :
The enzyme catalyzing the hydrolytic cleavage of 2,6-dihydroxypseudooxynicotine to 2,6-dihydroxypyridine and gamma-N-methylaminobutyrate was found to be encoded on pAO1 of Arthrobacter nicotinovorans. The new enzyme answers an old question about nicotine catabolism and may be the first C--C bond hydrolase that is involved in the biodegradation of a heterocyclic compound. |
PubMedSearch : Sachelaru_2005_J.Bacteriol_187_8516 |
PubMedID: 16321959 |
Gene_locus related to this paper: artni-Q93NG6 |
Gene_locus | artni-Q93NG6 |
Sachelaru P, Schiltz E, Igloi GL, Brandsch R (2005)
An alpha\/beta-fold C--C bond hydrolase is involved in a central step of nicotine catabolism by Arthrobacter nicotinovorans
Journal of Bacteriology
187 :8516
Sachelaru P, Schiltz E, Igloi GL, Brandsch R (2005)
Journal of Bacteriology
187 :8516