| Title : Muscular dystrophy with laminin deficiency decreases acetylcholinesterase activity in thymus of dystrophic Lama2dy mice - Sanchez_2005_Chem.Biol.Interact_157-158_431 |
| Author(s) : Sanchez del Campo L , Nieto-Ceron S , Munoz-Delgado E , Vidal CJ , Campoy FJ |
| Ref : Chemico-Biological Interactions , 157-158 :431 , 2005 |
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Abstract :
We have studied the effect of muscular dystrophy by merosin deficiency on mouse thymus acetyl- (AChE) and butyrylcholinesterase (BuChE). The organ contains AChE and BuChE activities. Merosin deficiency causes an important decrease (46%) in AChE specific activity. Thymus produces dimers, monomers and tetramers of AChE, and the three kinds of AChE mRNAs. The drop in AChE activity in dystrophic animals could affect the amount of ACh reaching cholinergic receptors in cells of lymphoid organs. |
| PubMedSearch : Sanchez_2005_Chem.Biol.Interact_157-158_431 |
| PubMedID: 16429580 |
Sanchez del Campo L, Nieto-Ceron S, Munoz-Delgado E, Vidal CJ, Campoy FJ (2005)
Muscular dystrophy with laminin deficiency decreases acetylcholinesterase activity in thymus of dystrophic Lama2dy mice
Chemico-Biological Interactions
157-158 :431
Sanchez del Campo L, Nieto-Ceron S, Munoz-Delgado E, Vidal CJ, Campoy FJ (2005)
Chemico-Biological Interactions
157-158 :431