Schmidt_1969_Science_165_1370

Reference

Title : Acetylcholine: release from neural tissue and identification by pyrolysis--gas chromatography - Schmidt_1969_Science_165_1370
Author(s) : Schmidt DE , Szilagyi PI , Alkon DL , Green JP
Ref : Science , 165 :1370 , 1969
Abstract :

Gas chromatographic analysis showed acetylcholine to be the only choline ester released from innervated longitudinal muscle of the guinea pigileum by electrical stimulation. The amount of acetylcholine measured by gas chromatography agreed almost exactly with that measured by bioassay. Denervated longitudinal muscle produced no acetylcholine, and treatment of the muscle with tetrodotoxin markedly reduced acetylcholine output. The method permits the recovery and quantitation of amounts of acetylcholine as low as 5 nanograms in 5 milliliters of tissue perfusates.

PubMedSearch : Schmidt_1969_Science_165_1370
PubMedID: 5807962

Related information

Citations formats

Schmidt DE, Szilagyi PI, Alkon DL, Green JP (1969)
Acetylcholine: release from neural tissue and identification by pyrolysis--gas chromatography
Science 165 :1370

Schmidt DE, Szilagyi PI, Alkon DL, Green JP (1969)
Science 165 :1370