| Title : Synthesis of New DPP-4 Inhibitors Based on a Novel Tricyclic Scaffold - Schwehm_2015_ACS.Med.Chem.Lett_6_324 |
| Author(s) : Schwehm C , Li J , Song H , Hu X , Kellam B , Stocks MJ |
| Ref : ACS Med Chem Lett , 6 :324 , 2015 |
|
Abstract :
A novel molecular scaffold has been synthesized, and its synthesis and incorporation into new analogues of biologically active molecules will be discussed. A comparison of the inhibitory activity of these compounds to the known type-2 diabetes compound (sitagliptin) against dipeptidyl peptidase-4 (DPP-4) will be shown. |
| PubMedSearch : Schwehm_2015_ACS.Med.Chem.Lett_6_324 |
| PubMedID: 25815154 |
Schwehm C, Li J, Song H, Hu X, Kellam B, Stocks MJ (2015)
Synthesis of New DPP-4 Inhibitors Based on a Novel Tricyclic Scaffold
ACS Med Chem Lett
6 :324
Schwehm C, Li J, Song H, Hu X, Kellam B, Stocks MJ (2015)
ACS Med Chem Lett
6 :324