Shafiq_2013_J.Asian.Nat.Prod.Res_15_286

Reference

Title : Bioactive phenolics from Seriphidium stenocephalum - Shafiq_2013_J.Asian.Nat.Prod.Res_15_286
Author(s) : Shafiq N , Riaz N , Ahmed S , Ashraf M , Ejaz SA , Ahmed I , Saleem M , Touseef MI , Tareen RB , Jabbar A
Ref : J Asian Nat Prod Res , 15 :286 , 2013
Abstract :

Chromatographic separation of the ethyl acetate soluble part of the methanolic extract from Seriphidium stenocephalum yielded three new compounds: stenocepflavone (1), stenocepflavan (2), and stenocephol (3), together with cirsimaritin (4), 5,7,5'-trihydroxy-3',4',6-trimethoxyflavone (5), 5,6,7,5'-tetrahydroxy-4'-methoxyflavone (6), and axillaroside (7). All isolates were characterized with the help of spectroscopic data including 1D, 2D NMR, and high resolution mass spectrometry and/or in comparison with the related compounds in literature. All compounds were tested for in vitro enzyme inhibitory activities against acetylcholinesterase, butyrylcholinesterase, and lipoxygenase. Compounds 1 and 4-7 exhibited significant activity against all the tested enzymes, whereas compounds 2 and 3 were found inactive.

PubMedSearch : Shafiq_2013_J.Asian.Nat.Prod.Res_15_286
PubMedID: 23421930

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Citations formats

Shafiq N, Riaz N, Ahmed S, Ashraf M, Ejaz SA, Ahmed I, Saleem M, Touseef MI, Tareen RB, Jabbar A (2013)
Bioactive phenolics from Seriphidium stenocephalum
J Asian Nat Prod Res 15 :286

Shafiq N, Riaz N, Ahmed S, Ashraf M, Ejaz SA, Ahmed I, Saleem M, Touseef MI, Tareen RB, Jabbar A (2013)
J Asian Nat Prod Res 15 :286