| Title : Identification of the herboxidiene biosynthetic gene cluster in Streptomyces chromofuscus ATCC 49982 - Shao_2012_Appl.Environ.Microbiol_78_2034 |
| Author(s) : Shao L , Zi J , Zeng J , Zhan J |
| Ref : Applied Environmental Microbiology , 78 :2034 , 2012 |
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Abstract :
The 53-kb biosynthetic gene cluster for the novel anticholesterol natural product herboxidiene was identified in Streptomyces chromofuscus ATCC 49982 by genome sequencing and gene inactivation. In addition to herboxidiene, a biosynthetic intermediate, 18-deoxy-herboxidiene, was also isolated from the fermentation broth of S. chromofuscus ATCC 49982 as a minor metabolite. |
| PubMedSearch : Shao_2012_Appl.Environ.Microbiol_78_2034 |
| PubMedID: 22247174 |
| Gene_locus related to this paper: strcw-h6up12 |
| Gene_locus | strcw-h6up12 |
Shao L, Zi J, Zeng J, Zhan J (2012)
Identification of the herboxidiene biosynthetic gene cluster in Streptomyces chromofuscus ATCC 49982
Applied Environmental Microbiology
78 :2034
Shao L, Zi J, Zeng J, Zhan J (2012)
Applied Environmental Microbiology
78 :2034