| Title : Spontaneous remission in canine myasthenia gravis: implications for assessing human MG therapies - Shelton_2001_Neurology_57_2139 |
| Author(s) : Shelton GD , Lindstrom JM |
| Ref : Neurology , 57 :2139 , 2001 |
|
Abstract :
The natural course of autoimmune canine MG was determined in 53 dogs with muscular weakness and a positive acetylcholine receptor antibody titer. Dogs were treated with anticholinesterase therapy, without immunosuppression. Spontaneous clinical and immunologic remission occurred in 47 of 53 dogs within an average of 6.4 months. Neoplasia was identified in the six dogs that did not spontaneously remit. This study questions the value of using canine MG in studies designed to assess the effect of immunotherapies. |
| PubMedSearch : Shelton_2001_Neurology_57_2139 |
| PubMedID: 11739846 |
Shelton GD, Lindstrom JM (2001)
Spontaneous remission in canine myasthenia gravis: implications for assessing human MG therapies
Neurology
57 :2139
Shelton GD, Lindstrom JM (2001)
Neurology
57 :2139