| Title : beta-Carboline binding to deoxycholate solubilized benzodiazepine receptors from calf cerebral cortex - Sherman-Gold_1981_Neurosci.Lett_26_325 |
| Author(s) : Sherman-Gold R , Dudai Y |
| Ref : Neuroscience Letters , 26 :325 , 1981 |
|
Abstract :
The beta-carbolines harmane and norharmane competitively inhibit [3H]flunitrazepam ([3H]FNZ) binding to deoxycholate-solubilized benzodiazepine receptors from calf cerebral cortex, with Ki in the micromolar range [3H]Propyl-beta-carboline-3-carboxylate ([3H]PrCC) binds to the soluble receptors with an affinity similar to its binding to particulate receptors (0.41 nM vs 0.48 nM, respectively). The component that binds [3H]PrCC displays a sedimentation profile on sucrose gradient centrifugation similar to that of [3H]FNZ binding component (sedimentation coefficient about 11S). |
| PubMedSearch : Sherman-Gold_1981_Neurosci.Lett_26_325 |
| PubMedID: 6895661 |
Sherman-Gold R, Dudai Y (1981)
beta-Carboline binding to deoxycholate solubilized benzodiazepine receptors from calf cerebral cortex
Neuroscience Letters
26 :325
Sherman-Gold R, Dudai Y (1981)
Neuroscience Letters
26 :325