| Title : New furoquinoline alkaloids from the leaves of Evodia lepta - Sichaem_2013_Fitoterapia_92C_270 |
| Author(s) : Sichaem J , Jirasirichote A , Sapasuntikul K , Khumkratok S , Sawasdee P , Do TM , Tip-Pyang S |
| Ref : Fitoterapia , 92C :270 , 2013 |
|
Abstract :
Three new furoquinoline alkaloids, leptanoines A-C (1-3) along with three known compounds (4-6) were isolated from the leaves of Evodia lepta. Their structures were identified by interpretation of their spectroscopic data as well as comparison with those reported in the literature. In addition, all isolated compounds were evaluated for their acetylcholinesterase (AChE) and butyrylcholinesterase (BChE) activities. Compound 4 showed the highest inhibitory activity towards BChE with an IC50 value of 47.9muM. On the other hand, Compound 5 showed the highest inhibitory activity towards AChE with an IC50 value of 69.1muM. |
| PubMedSearch : Sichaem_2013_Fitoterapia_92C_270 |
| PubMedID: 24333260 |
Sichaem J, Jirasirichote A, Sapasuntikul K, Khumkratok S, Sawasdee P, Do TM, Tip-Pyang S (2013)
New furoquinoline alkaloids from the leaves of Evodia lepta
Fitoterapia
92C :270
Sichaem J, Jirasirichote A, Sapasuntikul K, Khumkratok S, Sawasdee P, Do TM, Tip-Pyang S (2013)
Fitoterapia
92C :270