| Title : Hepatoprotective phenolic constituents of Rhodiola sachalinensis on tacrine-induced cytotoxicity in Hep G2 cells - Song_2003_Phytother.Res_17_563 |
| Author(s) : Song EK , Kim JH , Kim JS , Cho H , Nan JX , Sohn DH , Ko GI , Oh H , Kim YC |
| Ref : Phytother Res , 17 :563 , 2003 |
|
Abstract :
Two hepatoprotective phenolic compounds, kaempferol (2) and salidroside (4), were isolated from the roots of Rhodiola sachalinensis together with two inactive compounds cinnamyl alcohol (1) and daucosterol (3) based on the hepatoprotective activity against tacrine-induced cytotoxicity in human liver-derived Hep G2 cells. The EC(50) values of compounds 2 and 4 were 33.5 and 51.3 micro m, respectively. Silybin as a positive control showed an EC(50) value of 68.4 micro m. |
| PubMedSearch : Song_2003_Phytother.Res_17_563 |
| PubMedID: 12749001 |
Song EK, Kim JH, Kim JS, Cho H, Nan JX, Sohn DH, Ko GI, Oh H, Kim YC (2003)
Hepatoprotective phenolic constituents of Rhodiola sachalinensis on tacrine-induced cytotoxicity in Hep G2 cells
Phytother Res
17 :563
Song EK, Kim JH, Kim JS, Cho H, Nan JX, Sohn DH, Ko GI, Oh H, Kim YC (2003)
Phytother Res
17 :563