| Title : Genome expansion and gene loss in powdery mildew fungi reveal tradeoffs in extreme parasitism - Spanu_2010_Science_330_1543 |
| Author(s) : Spanu PD , Abbott JC , Amselem J , Burgis TA , Soanes DM , Stuber K , Ver Loren van Themaat E , Brown JK , Butcher SA , Gurr SJ , Lebrun MH , Ridout CJ , Schulze-Lefert P , Talbot NJ , Ahmadinejad N , Ametz C , Barton GR , Benjdia M , Bidzinski P , Bindschedler LV , Both M , Brewer MT , Cadle-Davidson L , Cadle-Davidson MM , Collemare J , Cramer R , Frenkel O , Godfrey D , Harriman J , Hoede C , King BC , Klages S , Kleemann J , Knoll D , Koti PS , Kreplak J , Lopez-Ruiz FJ , Lu X , Maekawa T , Mahanil S , Micali C , Milgroom MG , Montana G , Noir S , O'Connell RJ , Oberhaensli S , Parlange F , Pedersen C , Quesneville H , Reinhardt R , Rott M , Sacristan S , Schmidt SM , Schon M , Skamnioti P , Sommer H , Stephens A , Takahara H , Thordal-Christensen H , Vigouroux M , Wessling R , Wicker T , Panstruga R |
| Ref : Science , 330 :1543 , 2010 |
|
Abstract :
Powdery mildews are phytopathogens whose growth and reproduction are entirely dependent on living plant cells. The molecular basis of this life-style, obligate biotrophy, remains unknown. We present the genome analysis of barley powdery mildew, Blumeria graminis f.sp. hordei (Blumeria), as well as a comparison with the analysis of two powdery mildews pathogenic on dicotyledonous plants. These genomes display massive retrotransposon proliferation, genome-size expansion, and gene losses. The missing genes encode enzymes of primary and secondary metabolism, carbohydrate-active enzymes, and transporters, probably reflecting their redundancy in an exclusively biotrophic life-style. Among the 248 candidate effectors of pathogenesis identified in the Blumeria genome, very few (less than 10) define a core set conserved in all three mildews, suggesting that most effectors represent species-specific adaptations. |
| PubMedSearch : Spanu_2010_Science_330_1543 |
| PubMedID: 21148392 |
| Gene_locus related to this paper: blugr-d2cql4 , blug1-n1jlh9 , blug1-n1j5n4 , blug1-n1j9r9 , blug1-n1je34 , blug1-n1jkm5 , blug1-n1jhv6 , blug1-n1j8l0 , blug1-n1jqj7 , blug1-n1j543 |
Spanu PD, Abbott JC, Amselem J, Burgis TA, Soanes DM, Stuber K, Ver Loren van Themaat E, Brown JK, Butcher SA, Gurr SJ, Lebrun MH, Ridout CJ, Schulze-Lefert P, Talbot NJ, Ahmadinejad N, Ametz C, Barton GR, Benjdia M, Bidzinski P, Bindschedler LV, Both M, Brewer MT, Cadle-Davidson L, Cadle-Davidson MM, Collemare J, Cramer R, Frenkel O, Godfrey D, Harriman J, Hoede C, King BC, Klages S, Kleemann J, Knoll D, Koti PS, Kreplak J, Lopez-Ruiz FJ, Lu X, Maekawa T, Mahanil S, Micali C, Milgroom MG, Montana G, Noir S, O'Connell RJ, Oberhaensli S, Parlange F, Pedersen C, Quesneville H, Reinhardt R, Rott M, Sacristan S, Schmidt SM, Schon M, Skamnioti P, Sommer H, Stephens A, Takahara H, Thordal-Christensen H, Vigouroux M, Wessling R, Wicker T, Panstruga R (2010)
Genome expansion and gene loss in powdery mildew fungi reveal tradeoffs in extreme parasitism
Science
330 :1543
Spanu PD, Abbott JC, Amselem J, Burgis TA, Soanes DM, Stuber K, Ver Loren van Themaat E, Brown JK, Butcher SA, Gurr SJ, Lebrun MH, Ridout CJ, Schulze-Lefert P, Talbot NJ, Ahmadinejad N, Ametz C, Barton GR, Benjdia M, Bidzinski P, Bindschedler LV, Both M, Brewer MT, Cadle-Davidson L, Cadle-Davidson MM, Collemare J, Cramer R, Frenkel O, Godfrey D, Harriman J, Hoede C, King BC, Klages S, Kleemann J, Knoll D, Koti PS, Kreplak J, Lopez-Ruiz FJ, Lu X, Maekawa T, Mahanil S, Micali C, Milgroom MG, Montana G, Noir S, O'Connell RJ, Oberhaensli S, Parlange F, Pedersen C, Quesneville H, Reinhardt R, Rott M, Sacristan S, Schmidt SM, Schon M, Skamnioti P, Sommer H, Stephens A, Takahara H, Thordal-Christensen H, Vigouroux M, Wessling R, Wicker T, Panstruga R (2010)
Science
330 :1543