| Title : Allosteric modulation of the nicotinic acetylcholine receptor by physostigmine - Svobodova_2005_Ann.N.Y.Acad.Sci_1048_355 |
| Author(s) : Svobodova L , Krusek J , Hendrych T , Vyskocil F |
| Ref : Annals of the New York Academy of Sciences , 1048 :355 , 2005 |
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Abstract :
The action of physostigmine on mouse muscle nicotinic acetylcholine receptor expressed in the COS-7 cell line was studied by the patch-clamp technique. Physostigmine accelerated, by allosteric modulation, the rate of desensitization of whole cell currents induced by acetylcholine and decreased the maximal amplitude in concentration-dependent manner. |
| PubMedSearch : Svobodova_2005_Ann.N.Y.Acad.Sci_1048_355 |
| PubMedID: 16154951 |
Svobodova L, Krusek J, Hendrych T, Vyskocil F (2005)
Allosteric modulation of the nicotinic acetylcholine receptor by physostigmine
Annals of the New York Academy of Sciences
1048 :355
Svobodova L, Krusek J, Hendrych T, Vyskocil F (2005)
Annals of the New York Academy of Sciences
1048 :355