| Title : Tricorn protease--the core of a modular proteolytic system - Tamura_1996_Science_274_1385 |
| Author(s) : Tamura T , Tamura N , Cejka Z , Hegerl R , Lottspeich F , Baumeister W |
| Ref : Science , 274 :1385 , 1996 |
|
Abstract :
Large macromolecular assemblies have evolved as a means of compartmentalizing reactions in organisms lacking membrane-bounded compartments. A tricorn-shaped protease was isolated from the archaeon Thermoplasma and was shown to form a multisubunit proteolytic complex. The 120-kilodalton monomer assembled to form a hexameric toroid that could assemble further into a capsid structure. Tricorn protease appeared to act as the core of a proteolytic system; when it interacted with several smaller proteins, it displayed multicatalytic activities. |
| PubMedSearch : Tamura_1996_Science_274_1385 |
| PubMedID: 8910281 |
Tamura T, Tamura N, Cejka Z, Hegerl R, Lottspeich F, Baumeister W (1996)
Tricorn protease--the core of a modular proteolytic system
Science
274 :1385
Tamura T, Tamura N, Cejka Z, Hegerl R, Lottspeich F, Baumeister W (1996)
Science
274 :1385