Title : Binding of a Glycera convoluta neurotoxin to cholinergic nerve terminals triggers a Ca-dependent acetylcholine release - Thieffry_1984_J.Physiol.Paris_79_269 |
Author(s) : Thieffry M , Morel Ni , Manaranche R |
Ref : Journal de Physiologie (Paris) , 79 :269 , 1984 |
Abstract :
The venom glands of the annelid Glycera convoluta contain a neurotoxin which triggers ACh release from frog motor terminals and Torpedo synaptosomes. This neurotoxin binds to presynaptic, but not postsynaptic plasma membranes prepared from Torpedo electric organ. The binding site is an ectocellularly oriented protein. The binding does not require Ca. It is inhibited by pretreatment of the membrane by Concanavalin A. The toxin induced ACh release is Ca-dependent and inhibited by D 600. |
PubMedSearch : Thieffry_1984_J.Physiol.Paris_79_269 |
PubMedID: 6530669 |
Thieffry M, Morel Ni, Manaranche R (1984)
Binding of a Glycera convoluta neurotoxin to cholinergic nerve terminals triggers a Ca-dependent acetylcholine release
Journal de Physiologie (Paris)
79 :269
Thieffry M, Morel Ni, Manaranche R (1984)
Journal de Physiologie (Paris)
79 :269