Tonkopii_1976_Biull.Eksp.Biol.Med_82_947

Reference

Title : [Interaction of reversible inhibitors with the catalytic centers and allosteric sites of cholinesterases] - Tonkopii_1976_Biull.Eksp.Biol.Med_82_947
Author(s) : Tonkopii VD , Prozorovskii VB , Suslova IM
Ref : Biulleten Eksperimentalnoi Biologii i Meditsiny , 82 :947 , 1976
Abstract :

The kinetics of inhibition of the human red blood cell cholinesterase with galanthamine tacrine and oxazyl (ambenonium) and the effect of these drugs on chick, mouse, cat and rat blood plasma enzyme activity was studied. Galanthamine proved to bind with acetylcholinesterase in the anionic areas of the catalytic centres, oxazyl interacted in the area of the allosteric anionic site, and tacrin interacted with the hydrophobic areas of the enzyme.

PubMedSearch : Tonkopii_1976_Biull.Eksp.Biol.Med_82_947
PubMedID: 1026294

Related information

Citations formats

Tonkopii VD, Prozorovskii VB, Suslova IM (1976)
[Interaction of reversible inhibitors with the catalytic centers and allosteric sites of cholinesterases]
Biulleten Eksperimentalnoi Biologii i Meditsiny 82 :947

Tonkopii VD, Prozorovskii VB, Suslova IM (1976)
Biulleten Eksperimentalnoi Biologii i Meditsiny 82 :947