| Title : Comparison of the chromatographic characteristics of metabolites of tacrine hydrochloride in human serum and urine with those of in vitro metabolic products from hepatic microsomes - Truman_1991_Biochem.Pharmacol_42_956 |
| Author(s) : Truman CA , Ford JM , Roberts CJ |
| Ref : Biochemical Pharmacology , 42 :956 , 1991 |
|
Abstract :
There may be as many as five metabolites of THA in man, four corresponding to products in the rat. The study provides some evidence that one of major metabolites is 1-hydroxy-THA but lends no support to the putative oxidative deamination pathway. |
| PubMedSearch : Truman_1991_Biochem.Pharmacol_42_956 |
| PubMedID: 1867652 |
Truman CA, Ford JM, Roberts CJ (1991)
Comparison of the chromatographic characteristics of metabolites of tacrine hydrochloride in human serum and urine with those of in vitro metabolic products from hepatic microsomes
Biochemical Pharmacology
42 :956
Truman CA, Ford JM, Roberts CJ (1991)
Biochemical Pharmacology
42 :956