| Title : Whey proteins as source of dipeptidyl dipeptidase IV (dipeptidyl peptidase-4) inhibitors - Tulipano_2011_Peptides_32_835 |
| Author(s) : Tulipano G , Sibilia V , Caroli AM , Cocchi D |
| Ref : Peptides , 32 :835 , 2011 |
| Abstract : Preclinical and clinical studies suggest that whey proteins can reduce postprandial glucose levels and stimulate insulin release in healthy subjects and in subjects with type 2 diabetes by reducing dipeptidyl peptidase-4 (DPP-4) activity in the proximal bowel and hence increasing intact incretin levels. Our aim was to identify DPP-4 inhibitors among short peptides occurring in hydrolysates of beta-lactoglobulin, the major whey protein found in the milk of ruminants. We proved that the bioactive peptide Ile-Pro-Ala can be regarded as a moderate DPP-4 inhibitor. |
| ESTHER : Tulipano_2011_Peptides_32_835 |
| PubMedSearch : Tulipano_2011_Peptides_32_835 |
| PubMedID: 21256171 |
Tulipano G, Sibilia V, Caroli AM, Cocchi D (2011)
Whey proteins as source of dipeptidyl dipeptidase IV (dipeptidyl peptidase-4) inhibitors
Peptides
32 :835
Tulipano G, Sibilia V, Caroli AM, Cocchi D (2011)
Peptides
32 :835