Title : Pheromone binding and inactivation by moth antennae - Vogt_1981_Nature_293_161
Author(s) : Vogt RG , Riddiford LM
Ref : Nature , 293 :161 , 1981
Abstract :

The antennae of male silk moths are extremely sensitive to the female sex pheromone such that a male moth can find a female up to 4.5 km away. This remarkable sensitivity is due to both the morphological and biochemical design of these antennae. Along the branches of the plumose antennae are the sensilla trichodea, each consisting of a hollow cuticular hair containing two unbranched dendrites bathed in a fluid, the receptor lymph ,3. The dendrites and receptor lymph are isolated from the haemolymph by a barrier of epidermal cells which secreted the cuticular hair. Pheromone molecules are thought to diffuse down 100 A-wide pore tubules through the cuticular wall and across the receptor lymph space to receptors located in the dendritic membrane. To prevent the accumulation of residual stimulant and hence sensory adaptation, the pheromone molecules are subsequently inactivated in an apparent two-step process of rapid 'early inactivation' followed by much slower enzymatic degradation. The biochemistry involved in this sequence of events is largely unknown. We report here the identification of three proteins which interact with the pheromone of the wild silk moth Antheraea polyphemus: a pheromone-binding protein and a pheromone-degrading esterase, both uniquely located in the pheromone-sensitive sensilla; and a second esterase common to all cuticular tissues except the sensilla.

PubMedSearch : Vogt_1981_Nature_293_161
PubMedID: 18074618
Gene_locus related to this paper: antpo-odest , antpo-tegest

Related information

Substrate E6Z11-16Ac
Gene_locus antpo-odest    antpo-tegest

Citations formats

Vogt RG, Riddiford LM (1981)
Pheromone binding and inactivation by moth antennae
Nature 293 :161

Vogt RG, Riddiford LM (1981)
Nature 293 :161